Presentations

11/10-12/2018 American Heart Association Scientific Sessions, Chicago, IL
Frontiers in Science: Arrhythmia Research Summit
Bioengineering of cardiac structures 
Narutoshi Hibino (Invited), Chin Siang Ong (Presented)

CRISPR Interference to Correct Diseased 2D and 3D hiPSC-CMs With Calmodulinopathies
Chin Siang Ong1,2, Chen Yu Huang1, Jingnan Han1, Ijala Wilson1, Joe Boktor2, Narutoshi Hibino2, Gordon F Tomaselli1,3
1Division of Cardiology, The Johns Hopkins Hospital
2Division of Cardiac Surgery, Johns Hopkins Hospital
3Albert Einstein College of Medicine

A simple mold-based method to create biomaterial- free vascularized three-dimensional cardiac tissue
Hiroshi Matsushita, Yang Bai, Chin Siang Ong, Cecillia Lui, Enoch Yeung, Isaree Pitaktong, Takahiro Inoue, Narutoshi Hibino

11/6-9/2018 Southern Thoracic Surgical Association, Marco Island, FL
3D Printed Cardiac Patch Augments Angiogenesis and Reduced Scar Area Formation in Vivo
Enoch Yeung, Fukunishi Takuma, Yang Bai, Djahida Bedja, Isaree Pitaktong, Gunnar Mattson, Cecillia Lui, Chin Siang Ong, Hiroshi Matsushita, Taka Inoue, Narutoshi Hibino

11/9/2018 American Medical Association Research Symposium, National Harbor, MD
Novel Methodology for Generating Precardiac Organoids Enables Reproducible High Throughput Analysis of Cardiovascular Development
Lucy L. Nam1,2*, Matthew Miyamoto1*, Suraj Kannan1, Narutoshi Hibino2, Chulan Kwon1, Peter Andersen1
1. Johns Hopkins University Department of Medicine, Division of Cardiology, Maryland, USA. 2. Johns Hopkins University Department of Medicine, Division of Cardiac Surgery, Maryland, USA.

10/21/2018 Congenital Heart Surgeons’ Society Annual Meeting 2018, Chicago, IL
Mechanical Maturation of 3D-Printed Human Induced Pluripotent Stem Cell Derived Cardiomyocytes
Cecillia Lui, MD1, Yang Bai, MD1, Enoch Yeung, MD1, Seungman Park, PhD2, Yun Chen, PhD2, Chulan Kwon, MS, PhD3, Gordon Tomaselli, MD3, Luca A. Vricella, MD1, Narutoshi Hibino, MD1
1Division of Cardiac Surgery, The Johns Hopkins Hospital, Baltimore, MD
2Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD
3Division of Cardiology, The Johns Hopkins Hospital, Baltimore, MD
THE BEST RESIDENT PAPER AWARD

10/19/2018 Biomedical Engineering Society Annual Meeting, Atlanta, GA
Early Vascular Cells Improve Microvascularization within 3D Cardiac Spheroids
Isaree Pitaktong1, Cecillia Lui2, Justin Lowenthal1, Wei-Hung Jung3, Gunnar Mattson1, Yang Bai2, Enoch Yeung2, Chin Siang Ong2,
Yun Chen3, Sharon Gerecht4, Narutoshi Hibino2
1 Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA
2 Division of Cardiac Surgery, Johns Hopkins Hospital, Baltimore, MD, USA
3 Department of Mechanical Engineering, Johns Hopkins University, Baltimore, Maryland, USA
4 Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, USA

9/16/2018 THE INTERNATIONAL SOCIETY FOR APPLIED CARDIOVASCULAR BIOLOGY- 16TH BIENNIAL MEETING -BORDEAUX, FRANCE
A Novel Extruded Polyglycerol (Sebacate) and Polyglycolic Acid Vascular Graft.
Takuma Fukunishi, Cecillia Lui, Chin Siang Ong, Carissa Smoot, Seth Winner, Jeremy Harris, Peter Gabriele, Lakshmi Santhanam, Dan Berkowitz, Luca Vricella, Steven Lu, Narutoshi Hibino,

6/7/2018 Johns Hopkins Department of Surgery Research Day 
Mechanical Maturation of 3D-Printed Human Induced Pluripotent Stem Cell Derived Cardiomyocytes
Cecillia Lui, Seungman Park, Yun Chen, Chulan Kwon, Gordon Tomaselli, Narutoshi Hibino
George Zuidema, MD Award for Meritorious Laboratory Research

5/24-27/2018 The 26th Annual Meeting of the Asian Society for Cardiovascular and Thoracic Surgery, Moscow, Russia 
Different Biodegradation Rates of Tissue-Engineered Vascular Grafts in Small and Large Animal Models
Takuma Fukunishi, Chin Siang Ong, Pooja Yesantharao, Huaitao Zhang, Gunnar Mattson, Joe Boktor, Jed Johnson, Narutoshi Hibino

5/14/2018 Regenerative Medicine Seminar Series, US Food & Drug (FDA), Siver Spring, MD
Preclinical Study of Patient-Specific Tissue Engineering Vascular Graft Using 3D Printing Technology
Narutoshi Hibino (Invited Talk)

5/10/2018 9th annual Johns Hopkins Cardiovascular Research Retreat (4/20/2018) & 24th Talalay-Gott Award 
Mechanical Maturation of 3D-Printed Human Induced Pluripotent Stem Cell Derived Cardiomyocytes
Cecillia Lui, Seungman Park, Yun Chen, Chulan Kwon, Gordon Tomaselli, Narutoshi Hibino
  •   Winner (Announced 6/23/2018)

CRISPR interference to correct diseased 2D and 3D hiPSC-CMs with calmodulinopathies
Chin Siang Ong, Chen Yu Huang, Jingnan Han, Ijala Wilson, Joe Boktor, Narutoshi Hibino, Gordon Tomaselli

5/4/2018 12th Annual Nano-Bio Symposium, Johns Hopkins Whiting School of Engineering
3D Printed Biomaterial-Free Cardiac Patch Enhances Vasculization and Suppresses Scar Tissue Formation in Myocardial Infarction Model in vivo
Enoch Yeung, Takuma Fukunishi, Yang Bai, Isaree Pitaktong , Gunnar Mattson ,Chin Siang Ong, Cecillia Lui, Takahiro Inoue, Hiroshi Matsushita, Narutoshi Hibino

CRISPR interference to correct diseased 2D and 3D hiPSC-CMs with calmodulinopathies
Chin Siang Ong, Chen Yu Huang, Jingnan Han, Ijala Wilson, Joe Boktor, Narutoshi Hibino, Gordon Tomaselli

3/27/2018 Bioengineering 2017, Boston, MA
Cardiovascular Tissue Engineering Using 3D Printing Technology
Naurtoshi Hibino (Invited Talk)

3/16/2018 Johns Hopkins Department of Medicine Research Retreat
Paracrine effect of cardiac patch augments angiogenesis and reduces scar tissue formation in vivo
Enoch Yeung, Takuma Fukunishi, Yang Bai, Isaree Pitaktong , Gunnar Mattson , Chin Siang Ong, Cecillia Lui, Takahiro Inoue, Hiroshi Matsushita, Narutoshi Hibino
W. Leigh Thompson Excellence in Research Award

12/3-6/2017 TERMIS-Americas (TERMIS-AM) 8th Annual Conference and Exhibition (Charlotte, North Carolina)
Rapid and Well-Organized Extracellular Matrix Leads to Increased Tissue Transglutaminase in Arterial Tissue-Engineered Vascular Grafts
Takuma Fukunishi, MD1, Chin Siang Ong, MBBS1, Huaitao Zhang, BS1, Jochen Steppan, MD2, Cecillia Lui, MD1, Yang Bai, MD, PhD1, Takahiro Inoue, MD, PhD1, Enoch Yeung, MBBS1, Hiroshi Matsushita, MD1, Dan Berkowitz, MD2, Luca Vricella, MD1, Jed Johnson, PhD3, Lakshmi Santhanam, PhD2, Narutoshi Hibino, MD, PhD 1
1 Department of Cardiac Surgery, Johns Hopkins Hospital, Baltimore, MD
2 Department of Anesthesiology, Johns Hopkins Hospital, Baltimore, MD
3 Nanofiber Solution Inc, Columbus, OH

11/11-15/2017 American Heart Association Scientific Sessions, Anaheim, California
Cardiac Remuscularization using 3D Bioprinted Cardiac Patches (Oral)
Chin Siang Ong, Takuma Fukunishi, Isaree Pitaktong, Samantha Hardy, Huaitao Zhang, Chen Yu Huang, Luca Vricella, Gordon F Tomaselli, Narutoshi Hibino

10/25/2017 9th Annual Maryland Stem Cell Research Symposium, Hilton Baltimore
Adipose-derived Stem Cells Improve Cardiac Spheroid Viability by Angiogenesis (Poster)
Isaree Pitaktong1,2, Chin Siang Ong, MBBS1,2, Gunnar Matson1,2, Huaitao Zhang, BS1,
Takuma Fukunishi, MD1, Chen Yu Huang, PhD3, Cecillia Lui MD1, Narutoshi Hibino, MD, PhD1
1 Division of Cardiac Surgery, Johns Hopkins Hospital, Baltimore, Maryland, USA
2 Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA
3 Division of Cardiology, Johns Hopkins Hospital, Baltimore, Maryland, USA

10/22-23/2017 Congenital Heart Surgeons’ Society Annual Meeting 2017, Chicago, IL
Improvement of Electrophysiological and Morphological Characteristics of 3D Bioprinted Human Induced Pluripotent Stem Cell-Derived Cardiac Patches by Defined Factors
Chin Siang Ong1,2, Takuma Fukunishi1, Huaitao Zhang1, Chen Yu Huang2, Adriana Blazeski3, Deborah DiSilvestre2, Luca Vricella1, Leslie Tung3, Gordon Tomaselli2, Narutoshi Hibino1
1Division of Cardiac Surgery, Johns Hopkins Hospital, Baltimore, Maryland, USA, 2Division of Cardiology, Johns Hopkins Hospital, Baltimore, Maryland, USA, 3Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA

Designing Customized 3D Printed Models For Surgical Planning in Repair of Congenital Heart Defects
Sarah Chen1, Juan Garcia1, Luca Vricella2, Narutoshi Hibino2
1Johns Hopkins School of Medicine, Baltimore, MD, USA, 2Johns Hopkins Hospital, Baltimore, MD

10/13/2017 Lecture at BME, JHU
Biomaterials II: Host response and biomaterials applications.
Chapter 3.4. Biomaterials for vascular grafts
Narutoshi Hibino

9/15/2017 Progress in Scaffold-Free Biofabrication (Indianapolis, IN)
Symposium in 3D Bioprinting co-presented by IUPUI and Johns Hopkins University
“Bio 3D Printing for Cardiovascular Tissue Engineering”
Narutoshi Hibino (Invited Talk)

6/21-24/2017 43rd Annual Meeting of The Western Thoracic Surgical Association (Colorado Springs, CO)
Virtual Cardiac Surgery Planning to Improve Blood Flow Dynamics using 3D Image Processing
Chin Siang Ong1, Yue-Hin Loke2, Dominik Siallagan3, Laura Olivieri2, Diane de Zélicourt4, William Moore3, Marianne Schmid Daners5, Mirko Meboldt5, Luca Vricella1, Axel Krieger3, Narutoshi Hibino1
1Division of Cardiac Surgery, Johns Hopkins Hospital, Baltimore, MD;2Division of Cardiology, Children’s National Health System, Washington DC, DC;3Sheikh Zayed Institute for Pediatric Surgical Innovation, Children’s National Health System, Washington DC, DC;4Institute of Physiology, University of Zürich, Zürich, Switzerland5Institute of Design, Materials and Fabrication, Eidgenössische Technische Hochschule Zürich, Zürich, Switzerland

6/9/2017 Department of Pathology Ground Round, Johns Hopkins University
Narutoshi Hibino: “Cardiovascular Tissue Engineering using 3D Printing Technology” (Invited Talk)

6/9/2017 39th Biennial Meeting of the Johns Hopkins Medical and Surgical Association and Reunion Weekend
Narutoshi Hibino: “Bio 3D Printing of the Heart”, Johns Hopkins University, Baltimore, MD (Invited Talk)
Chin Siang Ong: 3D bioprinting of cardiac tissue (Poster)

6/5-6/2017 Third international symposium on vascular tissue engineering (Columbus, OH)
Novel Ultra-Thin PGA Fiber Textile Technology in Small-Diameter Tissue Engineered Arterial Grafts
Takuma Fukunishi, Chin Siang Ong, Huaitao Zhang, Sandeep Jandu, Jochen Steppan, Lakshmi Santhanam, Dan Berkowitz, Luca Vricella, Carissa Smoot, Seth Winner, Jeremy Harris, Peter Gabriele, Steven Lu, Narutoshi Hibino

5/24/2017 Johns Hopkins Department of Surgery Research Day
Narutoshi Hibino: 3D bioprinting of cardiac tissue (Invited Lecture)
Chin Siang Ong: 3D bioprinting of cardiac tissue (Poster)

5/23/2017 Johns Hopkins Graduate Student Association (GSA) Poster Session
Chin Siang Ong: 3D bioprinting of cardiac tissue (Poster)
•   1st Place (Category: 1st/2nd year Graduate Students)

5/19/2017 Johns Hopkins Heart and Vascular Institute 8th Annual Cardiovascular Research Retreat
Narutoshi Hibino: 3D bioprinting of cardiac tissue (Invited Lecture)
Chin Siang Ong: 3D bioprinting of cardiac tissue (Poster)

5/11/2017 Johns Hopkins 23rd Annual Talalay-Gott Cardiac Research Prize Presentations
Chin Siang Ong: 3D bioprinting of cardiac tissue
   •   Winner (Announced 6/24/2017)
Huaitao Zhang: TEVGs

5/5/2017 Johns Hopkins Nano-Bio Symposium, Baltimore, MD
“Challenge to Cardiovascular Disease using 3D Printing and Tissue Engineering”
Narutoshi Hibino (Invited Talk)

3/17/2017 Bioengineering 2017, Boston, MA
“Cardiovascular Tissue Engineering Using 3D Printing Technology”
Narutoshi Hibino (Invited Talk)

3/7/2017 Johns Hopkins Department of Medicine 2017 Research Retreat
3D bioprinting of cardiac tissue
Chin Siang Ong

1/30/2017 Arab Health 3D Medical Printing Conference, Dubai, UAE
“Cardiovascular application of 3D printing technology”
Narutoshi Hibino (Invited Talk)

12/5/2016 International Conference for Innovations 2016, Tel Aviv, Israel
“Novel Textile Technology for Small Diameter Tissue Engineered Arterial Grafts” Narutoshi Hibino, Takuma Fukunishi, Chin Siang Ong, Huaitao Zhang, Jochen Steppan, Lakshmi Santhanam, Dan Berkowitz, Luca Vricella, Carissa Smoot, Seth Winner, Steven Lu, Jeremy Harris

11/12-16/2016 American Heart Association Scientific Sessions, New Orleans, Louisiana “Novel Stem Cell Therapy for Heart Failure Using 3D Printed Cardiac Tissue”
Chin Siang Ong, Takuma Fukunishi, Adriana Blazeski, Huaitao Zhang, Andrew R. L. Nashed, Luca Vricella, John Conte, Leslie Tung, Gordon F. Tomaselli, Narutoshi Hibino
American Heart Association Council on Cardiovascular Surgery and Anesthesia (CVSA) Top Ten Abstract Travel Grant

10/23-24/2016 Congenital Heart Surgeons’ Society Annual Meeting 2016, Chicago, IL Biomaterial-Free Cardiac Tissue Created From Human Induced Pluripotent Cells Using Bio-3D Printer
Chin Siang Ong, Takuma Fukunishi, Adriana Blazeski, Huaitao Zhang, Andrew R. L. Nashed, Luca Vricella, John Conte, Leslie Tung, Gordon F. Tomaselli, Narutoshi Hibino
John A. Hawkins Top Scoring Abstract Award

Novel PGA Fiber Textile Technology and Immunomodulation with PGS Coating For Improved Neotissue Formation Of Small-Diameter Tissue Engineered Arterial Grafts Takuma Fukunishi, Huaitao Zhang, Chin Siang Ong, Andrew Nashed, Jochen Steppan, Lakshmi Santhanam, Dan Berkowitz, Steven Lu, Luca Vricella, Narutoshi Hibino

10/20/2016 Children’s National Heart Institute Research Seminar, Washington, DC”
“Cardiovascular tissue engineering using 3D printing technology”
Narutoshi Hibino (Invited Talk)

10/11/2016 The Johns Hopkins Institute for Cell Engineering seminar, Baltimore, MD
“Cardiovascular tissue engineering using 3D printing technology”
Narutoshi Hibino (Invited Talk)

9/7-10/2016 15th Biennial Meeting, International Society for Applied Cardiovascular Biology (ISACB), Banff, Alberta, Canada
Cell Seeding of a Novel Electrospun Vascular Graft Prevents Stenosis in a Mouse Model
Takuma Fukunishi, Cameron Best, Tadahisa Sugiura, Christopher Breuer, Toshiharu Shinoka, Jed Johnson, Narutoshi Hibino
The Young Investigator Award Finalist

6/22-25/2016 42th Annual Meeting of Western Thoracic Surgical Association, Waikoloa, Hawaii
Preclinical Study of Patient-Specific Cell-free Nanofiber TEVGs Using 3D Printing in a Sheep Model
Takuma Fukunishi, Cameron A. Best, Tadahisa Sugiura, Justin Opfermann, Toshiharu Shinoka, Christopher K. Breuer, Axel Krieger, Jed Johnson, and Narutoshi Hibino

6/3/2016 Johns Hopkins Heart and Vascular Institute’s 7th Annual Cardiovascular Research Retreat
Preclinical Study of Patient-Specific Cell-free Nanofiber TEVGs Using 3D Printing in a Sheep Model
Takuma Fukunishi, Cameron A. Best, Tadahisa Sugiura, Justin Opfermann, Toshiharu Shinoka, Christopher K. Breuer, Axel Krieger, Jed Johnson, and Narutoshi Hibino

5/26/2016 3rd Annual Johns Hopkins Postdoctoral Retreat
Preclinical Study of Patient-Specific Cell-free Nanofiber TEVGs Using 3D Printing in a Sheep Model
Takuma Fukunishi, Cameron A. Best, Tadahisa Sugiura, Justin Opfermann, Toshiharu Shinoka, Christopher K. Breuer, Axel Krieger, Jed Johnson, and Narutoshi Hibino

5/23/2016 8th Maryland Stem Cell Research Symposium, Bethesda, MD
A Novel Scaffold-free iPSC-based 3D-printing Approach to Treatment of Heart Failure
Chin Siang Ong, Narutoshi Hibino, Gordon F. Tomaselli

4/29/2016 10th Johns Hopkins University Nano-Bio Symposium
A Novel Scaffold-free iPSC-based 3D-printing Approach to Treatment of Heart Failure
Chin Siang Ong, Narutoshi Hibino, Gordon F. Tomaselli

12/3/2015 The International Society for Applied Cardiovascular Biology 2015 European Meeting, Nuremberg, Germany
“Small-Diameter Tissue-Engineered Vascular Grafts Using Electrospun PCL/Chitosan Nanofiber Scaffolds in Sheep Model”
Takuma Fukunishi, Cameron A. Best,  Tadahisa Sugiura, Shoji Toshihiro, Toshiharu Shinoka, Christopher K. Breuer, Jed Johnson, Narutoshi Hibino

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